SB 415286

目录号: A11061

GSK-3 inhibitor

SB 415286 Chemical Structure

CAS NO. 264218-23-7

SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM.

库存: 现货

规格 价格 数量
10 mg
¥ 900.00
25 mg
¥ 1,800.00
50 mg
¥ 3,200.00
100 mg
¥ 5,800.00
10mM * 1mL in DMSO
¥ 910.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM.
Targets
GSK-3α GSK-3β
78 nM~78 nM
In vitro DMSO 72 mg/mL (200.15 mM)
Water <1 mg/mL (<1 mM)
Ethanol 72 mg/mL (200.15 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.8 mL 139 mL 278.01 mL
0.5 mM 5.56 mL 27.8 mL 55.6 mL
1 mM 2.78 mL 13.9 mL 27.8 mL
5 mM 0.56 mL 2.78 mL 5.56 mL

*The above data is based on the productmolecular weight 359.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11061
MECHANISM OF ACTION Inhibitor
M. Wt 359.7
Formula C16H10ClN3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 264218-23-7
Synonyms SB-415286, SB415286
SMILES C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl)[N+](=O)[O-]

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