SB 431542
SB 431542 是一种强效且特异性的转化生长因子-β超家族类型 I ALK 受体 ALK4、ALK5 和 ALK7 的抑制剂。
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Adooq用户使用SB 431542发表的5篇文献
生物活性
| Discription | SB 431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I ALK receptors ALK4, ALK5, and ALK7 . | |||||
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产品信息
| 目录号 | A10826 |
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| 分子式 | C22H16N4O3 |
| 分子量 | 384.4 |
| CAS号 | 301836-41-9 |
| SMILES | C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5 |
| 其他名称 | SB-431542, SB431542 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 75 mg/mL (195.11 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (7.8 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+ddH2O | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.01 mL | 130.07 mL | 260.15 mL |
| 0.5 mM | 5.2 mL | 26.01 mL | 52.03 mL |
| 1 mM | 2.6 mL | 13.01 mL | 26.01 mL |
| 5 mM | 0.52 mL | 2.6 mL | 5.2 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 301836-41-9 | 301836-41-9 供应商 | 301836-41-9 花费 | 301836-41-9 生产商 | 订购 301836-41-9 | 301836-41-9 代理商