SB-505124

目录号: A11157

ALK5 抑制剂

SB-505124

SB-505124 Chemical Structure

CAS NO. 694433-59-5

SB-505124是转化生长因子-βI型受体(ALK5),ALK4和ALK7的选择性抑制剂(ALK5和ALK4的IC50值分别为47和129 nM)。

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
25 mg
¥ 2,200.00
50 mg
¥ 4,000.00
100 mg
¥ 7,200.00
10mM * 1mL in DMSO
¥ 990.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SB-505124是转化生长因子-βI型受体(ALK5),ALK4和ALK7的选择性抑制剂(ALK5和ALK4的IC50值分别为47和129 nM)。
靶点信息
ALK5 (Cell-free assay) ALK4 (Cell-free assay)
47 nM129 nM
In vitro (25°C) DMSO 67 mg/mL (199.76 mM)
Water <1 mg/mL (<1 mM)
Ethanol 67 mg/mL (199.76 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.82 mL 149.08 mL 298.15 mL
0.5 mM 5.96 mL 29.82 mL 59.63 mL
1 mM 2.98 mL 14.91 mL 29.82 mL
5 mM 0.6 mL 2.98 mL 5.96 mL

*The above data is based on the productmolecular weight 335.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11157
作用机制 Inhibitor (抑制剂)
M. Wt 335.4
Formula C20H21N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 694433-59-5
Synonyms SB505124
SMILES CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4

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