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SB-674042是有效的选择性非肽orexin OX1受体拮抗剂（Kd = 3.76 nM），对OX1的选择性比OX2受体高100倍。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.3 mL | 111.48 mL | 222.96 mL |
| 0.5 mM | 4.46 mL | 22.3 mL | 44.59 mL |
| 1 mM | 2.23 mL | 11.15 mL | 22.3 mL |
| 5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
*The above data is based on the productmolecular weight 448.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15233 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 448.51 |
| Formula | C24H21FN4O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 483313-22-0 |
| Synonyms | SB 674042, SB674042 |
| SMILES | CC1=NC(=C(S1)C2=CC=CC=C2F)C(=O)N3CCCC3CC4=NN=C(O4)C5=CC=CC=C5 |
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