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SB-674042

OX1 receptor 拮抗剂

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产品目录号: A15233

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SB-674042 5mg A15233-5
¥ 940.00
SB-674042 10mg A15233-10
¥ 1,600.00
SB-674042 50mg A15233-50
¥ 4,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.

SB-674042

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Chemical Information

目录号 A15233
Mechanism of action Antagonist
分子量 448.51
化学分子式 C24H21FN4O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 483313-22-0
Synonyms SB 674042, SB674042
SMILES code CC1=NC(=C(S1)C2=CC=CC=C2F)C(=O)N3CCCC3CC4=NN=C(O4)C5=CC=CC=C5
化学名称 [5-(2-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]-[(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]pyrrolidin-1-yl]methanone

生物活性

Description
SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.48 mL 222.96mL
0.5 mM 4.46 mL 22.3 mL 44.59 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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