SB-742457

目录号: A14092

5-HT6 receptor antagonist

SB-742457

SB-742457 Chemical Structure

CAS NO. 607742-69-8

SB-742457 is a selective 5-HT6 receptor antagonist with cognition, memory, and learning-enhancing effects.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,500.00
25 mg
¥ 3,000.00
10mM * 1mL in DMSO
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SB-742457 is a selective 5-HT6 receptor antagonist with cognition, memory, and learning-enhancing effects.
Targets
5-HT6
9.63(pKi)
In vitro (25°C) DMSO 78 mg/mL (220.68 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (5.65 mM)
In vivo 2% DMSO, 48% PEG300, 2% Tween 80 and 48% water 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.29 mL 141.47 mL 282.93 mL
0.5 mM 5.66 mL 28.29 mL 56.59 mL
1 mM 2.83 mL 14.15 mL 28.29 mL
5 mM 0.57 mL 2.83 mL 5.66 mL

*The above data is based on the productmolecular weight 353.444. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A14092
MECHANISM OF ACTION Antagonist
M. Wt 353.444
Formula C19H19N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 607742-69-8
Synonyms GSK 742457, SB742457, SB 742457, GSK742457, SB-742,457
SMILES C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4

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