SB225002

目录号: A14209

CXCR2 antagonist

SB225002

SB225002 Chemical Structure

CAS NO. 182498-32-4

SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, > 150-fold selectivity over the other 7-TMRs tested.

库存: 现货

规格 价格 数量
10 mg
¥ 700.00
25 mg
¥ 1,400.00
50 mg
¥ 2,200.00
10mM * 1mL in DMSO
¥ 650.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, > 150-fold selectivity over the other 7-TMRs tested.
Targets
CXCR2
22 nM
In vitro DMSO 70 mg/mL (198.78 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL heating (8.51 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.4 mL 141.99 mL 283.98 mL
0.5 mM 5.68 mL 28.4 mL 56.8 mL
1 mM 2.84 mL 14.2 mL 28.4 mL
5 mM 0.57 mL 2.84 mL 5.68 mL

*The above data is based on the productmolecular weight 352.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A14209
MECHANISM OF ACTION Antagonist
M. Wt 352.14
Formula C13H10BrN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 182498-32-4
Synonyms SB-225002, SB 225002
SMILES C1=CC=C(C(=C1)NC(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])O)Br

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