SB590885

目录号: A10829

B-Raf Inhibitor

SB590885

SB590885 Chemical Structure

CAS NO. 405554-55-4

SB590885 is a selective small-molecule inhibitor of the B-Raf kinase and Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,360.00
50 mg
¥ 4,500.00
100 mg
¥ 7,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SB590885 is a selective small-molecule inhibitor of the B-Raf kinase and Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively.
Targets
B-Raf (Cell-free assay)
0.16 nM(Ki)
In vitro (25°C) DMSO 5 mg/mL (11.02 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 2% Cremophor EL, 2% N,N-dimethylacetamide, pH 5.0 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.05 mL 110.25 mL 220.51 mL
0.5 mM 4.41 mL 22.05 mL 44.1 mL
1 mM 2.21 mL 11.03 mL 22.05 mL
5 mM 0.44 mL 2.21 mL 4.41 mL

*The above data is based on the productmolecular weight 453.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10829
MECHANISM OF ACTION Inhibitor
M. Wt 453.5
Formula C27H27N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 405554-55-4
Synonyms SB-590885
SMILES CN(C)CCOC1=CC=C(C=C1)C2=N/C(=C\3/C=CC4=C(CCC4=C3)N=O)/C(=C5C=CNC=C5)N2

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