SB590885

Name: SB590885
SKU: A10829
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A10829

B-Raf 抑制剂

SB590885 是一种选择性的小分子抑制剂，针对 B-Raf 激酶，其 Ki app 值分别为 B-Raf 和 c-Raf 的 0.16 nM 和 1.72 nM。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥560.00	现货
10mg	¥875.00	现货
25mg	¥1,820.00	现货
50mg	¥3,115.00	现货
100mg	¥5,180.00	现货
*10mM 1mL in DMSO**	¥980.00	现货
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Data Sheet

SDS

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生物活性

Discription

SB590885 is a selective small-molecule inhibitor of the B-Raf kinase and Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10829
分子式	C27H27N5O2
分子量	453.5
CAS号	405554-55-4
SMILES	CN(C)CCOC1=CC=C(C=C1)C2=N/C(=C\3/C=CC4=C(CCC4=C3)N=O)/C(=C5C=CNC=C5)N2
其他名称	SB-590885
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	5 mg/mL (11.02 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% Cremophor EL, 2% N,N-dimethylacetamide, pH 5.0	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.05 mL	110.25 mL	220.51 mL
0.5 mM	4.41 mL	22.05 mL	44.1 mL
1 mM	2.21 mL	11.03 mL	22.05 mL
5 mM	0.44 mL	2.21 mL	4.41 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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