SB590885

目录号: A10829

B-Raf 抑制剂

SB590885

SB590885 Chemical Structure

CAS NO. 405554-55-4

SB590885是B-Raf激酶的选择性小分子抑制剂,B-Raf和c-Raf的Ki app值分别为0.16和1.72 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,360.00
50 mg
¥ 4,500.00
100 mg
¥ 7,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SB590885是B-Raf激酶的选择性小分子抑制剂,B-Raf和c-Raf的Ki app值分别为0.16和1.72 nM。
靶点信息
B-Raf (Cell-free assay)
0.16 nM(Ki)
In vitro (25°C) DMSO 5 mg/mL (11.02 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% Cremophor EL, 2% N,N-dimethylacetamide, pH 5.0 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.05 mL 110.25 mL 220.51 mL
0.5 mM 4.41 mL 22.05 mL 44.1 mL
1 mM 2.21 mL 11.03 mL 22.05 mL
5 mM 0.44 mL 2.21 mL 4.41 mL

*The above data is based on the productmolecular weight 453.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10829
作用机制 Inhibitor (抑制剂)
M. Wt 453.5
Formula C27H27N5O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 405554-55-4
Synonyms SB-590885
SMILES CN(C)CCOC1=CC=C(C=C1)C2=N/C(=C\3/C=CC4=C(CCC4=C3)N=O)/C(=C5C=CNC=C5)N2

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