|Mechanism of action||Inhibitor|
|储存方式||at -20°C 2 years|
|SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.|
|Solubility (25°C) *||In vitro||DMSO||72 mg/mL (200.84 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||27 mg/mL (75.31 mM)|
|In vivo||1% DMSO/30% polyethylene glycol/1% Tween 80||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||27.89 mL||139.47 mL||278.94mL|
|0.5 mM||5.58 mL||27.89 mL||55.79 mL|
|1 mM||2.79 mL||13.95 mL||27.89 mL|
|5 mM||0.56 mL||2.79 mL||5.58 mL|
*The above data is based on the productmolecular weight 358.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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