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SB939 ( Pracinostat )

HDAC 抑制剂

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产品目录号: A10830


产品名 目录号 价格 数量
SB939 5mg A10830-5
¥ 900.00
SB939 10mg A10830-10
¥ 1,300.00
SB939 50mg A10830-50
¥ 4,000.00
SB939 100mg A10830-100
¥ 7,200.00
SB939 10mM * 1mL in DMSO A10830-10mM-D
¥ 1,240.00



SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.

SB939 ( Pracinostat )




顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A10830
Mechanism of action Inhibitor
分子量 358.5
化学分子式 C20H30N4O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 929016-96-6
Synonyms Pracinostat, SB-939
化学名称 3-​[2-​butyl-​1-​[2-​(diethylamino)ethyl]-​1H-​benzimidazol-​5-​yl]-​N-​hydroxy-​2E-​propenamide


SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.
Target Value
HDAC10IC50: 40nM
HDAC3IC50: 43nM
HDAC5IC50: 47nM
HDAC1IC50: 49nM
HDAC4IC50: 56nM
HDAC9IC50: 70nM
HDAC11IC50: 93nM
HDAC2IC50: 96nM
HDAC7IC50: 137nM
HDAC8IC50: 140nM
HDAC6IC50: 1.008μM
SIRT1IC50: >100μM


Solubility (25°C) * In vitro DMSO 72 mg/mL (200.84 mM)
Water <1 mg/mL (<1 mM)
Ethanol 27 mg/mL (75.31 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.89 mL 139.47 mL 278.94mL
0.5 mM 5.58 mL 27.89 mL 55.79 mL
1 mM 2.79 mL 13.95 mL 27.89 mL
5 mM 0.56 mL 2.79 mL 5.58 mL

*The above data is based on the productmolecular weight 358.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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