SB939 ( Pracinostat )

Name: SB939 ( Pracinostat )
SKU: A10830
Price: 595 CNY
Rating: 5 (1 reviews)

目录号: A10830

HDAC 抑制剂

1 篇发表文献

SB939 是一种口服 HDAC 抑制剂，选择性针对 I 类、II 类和 IV 类 HDAC，并在体外 HDAC1 活性测定中显示出 77 nM 的 IC50 值。

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Grouped product items
规格	价格	库存
5mg	¥595.00	现货
10mg	¥875.00	现货
25mg	¥1,750.00	现货
50mg	¥2,765.00	现货
100mg	¥5,005.00	现货
*10mM 1mL in DMSO**	¥868.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用SB939 ( Pracinostat )发表的1篇文献

Giovanni Bocci, .et al. , ACS Pharmacol Transl Sci, 2020, Oct 14

生物活性

Discription

SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10830
分子式	C20H30N4O2
分子量	358.5
CAS号	929016-96-6
SMILES	CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)/C=C/C(=O)NO
其他名称	Pracinostat, SB-939
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	68 mg/mL (189.68 mM)
	Water	Insoluble
	Ethanol	26 mg/mL (72.52 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.89 mL	139.47 mL	278.94 mL
0.5 mM	5.58 mL	27.89 mL	55.79 mL
1 mM	2.79 mL	13.95 mL	27.89 mL
5 mM	0.56 mL	2.79 mL	5.58 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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