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SBE 13 HCl

促销

PLK 抑制剂

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产品目录号: A14426

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SBE 13 HCl 10mg A14426-10
¥ 800.00
SBE 13 HCl 25mg A14426-25
¥ 1,600.00
SBE 13 HCl 50mg A14426-50
¥ 3,000.00
SBE 13 HCl 10mM * 1mL in DMSO A14426-10mM-D
¥ 1,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SBE 13 HCl is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively).

SBE 13 HCl

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Chemical Information

目录号 A14426
Mechanism of action Inhibitor
分子量 479.4
化学分子式 C24H27ClN2O4.HC
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1052532-15-6
Synonyms SBE-13, SBE 13
SMILES code COC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl
化学名称 N-[[4-[(6-Chloro-3-pyridinyl)methoxy]-3-methoxyphenyl]methyl]-3,4-dimethoxybenzeneethanamine hydrochloride

生物活性

Description
SBE 13 HCl is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively).
Targets
PLK1 PLK3 PLK2
200 pM875 nM>66 μM

溶解性

Solubility (25°C)* In vitro DMSO 95 mg/mL (198.16 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.86 mL 104.3 mL 208.59mL
0.5 mM 4.17 mL 20.86 mL 41.72 mL
1 mM 2.09 mL 10.43 mL 20.86 mL
5 mM 0.42 mL 2.09 mL 4.17 mL

*The above data is based on the productmolecular weight 479.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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