SBI-0206965

目录号: A15795

ULK1 抑制剂

SBI-0206965

SBI-0206965 Chemical Structure

CAS NO. 1884220-36-3

SBI-0206965是一种有效的,选择性的且细胞可渗透的自噬激酶ULK1抑制剂,对于ULK1激酶活性,IC50为108 nM;对于高度相关的激酶ULK2,IC50为711 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,800.00
25 mg
¥ 3,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SBI-0206965是一种有效的,选择性的且细胞可渗透的自噬激酶ULK1抑制剂,对于ULK1激酶活性,IC50为108 nM;对于高度相关的激酶ULK2,IC50为711 nM。
In vitro DMSO 90 mg/mL (183.92 mM)
Water Insoluble
Ethanol Warmed: 9 mg/mL (18.39 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.44 mL 102.18 mL 204.37 mL
0.5 mM 4.09 mL 20.44 mL 40.87 mL
1 mM 2.04 mL 10.22 mL 20.44 mL
5 mM 0.41 mL 2.04 mL 4.09 mL

*The above data is based on the productmolecular weight 489.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15795
作用机制 Inhibitor (抑制剂)
M. Wt 489.32
Formula C21H21BrN4O5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1884220-36-3
Synonyms SBI 0206965, SBI0206965
SMILES CNC(=O)C1=CC=CC=C1OC2=NC(=NC=C2Br)NC3=CC(=C(C(=C3)OC)OC)OC

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