SBI-115
目录号: A17235
GPCR19 拮抗剂
SBI-115 是一种 TGR5(GPCR19)拮抗剂。SBI-115 通过抑制 TGR5 减少多囊肝病的肝囊肿生成。
| Discription | SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5. |
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| 目录号 | A17235 |
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| 分子式 | C14H13ClN2O4S |
| 分子量 | 340.778 |
| CAS号 | 882366-16-7 |
| SMILES | O=C(C1=NC(S(=O)(CC)=O)=NC=C1Cl)OC2=CC=CC(C)=C2 |
| 其他名称 | SBI 115; SBI115; |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 58 mg/mL (170.2 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.34 mL | 146.72 mL | 293.45 mL |
| 0.5 mM | 5.87 mL | 29.34 mL | 58.69 mL |
| 1 mM | 2.93 mL | 14.67 mL | 29.34 mL |
| 5 mM | 0.59 mL | 2.93 mL | 5.87 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2