SC-514

Name: SC-514
SKU: A12746
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A12746

IκB/IKK 抑制剂

SC-514 是一种口服活性、ATP竞争性的 IKKβ抑制剂（IC50 = 3 - 12 μM），相较于其他28种激酶（包括JNK、p38、MK2和ERK）显示出超过10倍的选择性。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
25mg	¥490.00	现货
50mg	¥770.00	现货
100mg	¥1,190.00	现货
500mg	¥3,115.00	现货
*10mM 1mL in DMSO**	¥175.00	现货
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Data Sheet

SDS

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生物活性

Discription

SC-514 is an orally active, ATP-competitive IKKβ inhibitor (IC50 = 3 - 12 μM) that displays > 10-fold selectivity over 28 other kinases including JNK, p38, MK2 and ERK.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12746
分子式	C9H8N2OS2
分子量	224.3
CAS号	354812-17-2
SMILES	C1=CSC=C1C2=CC(=C(S2)C(=O)N)N
其他名称	SC514, SC 514
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	41 mg/mL (182.79 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	44.58 mL	222.92 mL	445.83 mL
0.5 mM	8.92 mL	44.58 mL	89.17 mL
1 mM	4.46 mL	22.29 mL	44.58 mL
5 mM	0.89 mL	4.46 mL	8.92 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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