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SC75741

NF-??B 抑制剂

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产品目录号: A14278

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SC75741 10mg A14278-10
¥ 1,200.00
SC75741 25mg A14278-25
¥ 2,200.00
SC75741 50mg A14278-50
¥ 3,800.00
SC75741 10mM * 1mL in DMSO A14278-10mM-D
¥ 1,270.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SC75741 is a potent NF-??B inhibitor with EC50 of 200 nM.

SC75741

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Chemical Information

目录号 A14278
Mechanism of action Inhibitor
分子量 565.67
化学分子式 C29H23N7O2S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 913822-46-5
Synonyms SC 75741
SMILES code C1CN(CCC1C2=NC(=CS2)C(=O)NC3=NC4=C(N3)C=C(C=C4)C(=O)C5=CC=CC=C5)C6=NC=NC7=C6SC=C7
化学名称 4-Thiazolecarboxamide, N-(6-benzoyl-1H-benzimidazol-2-yl)-2-(1-thieno[3,2-d]pyrimidin-4-yl-4-piperidinyl)-

生物活性

Description
SC75741 is a potent NF-??B inhibitor with EC50 of 200 nM.
Targets
NF-κB
200 nM(EC50)

溶解性

Solubility (25°C)* In vitro DMSO 35 mg/mL heating (61.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.68 mL 88.39 mL 176.78mL
0.5 mM 3.54 mL 17.68 mL 35.36 mL
1 mM 1.77 mL 8.84 mL 17.68 mL
5 mM 0.35 mL 1.77 mL 3.54 mL

*The above data is based on the productmolecular weight 565.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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