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SC79

目录号: A15541
Akt phosphorylation activator
SC79 是一种 AKT 激活剂。SC79 与 Akt 的 plecktrin homology (PH) 域 结合,模拟 PtdIns(3,4,5)P3 的结合,以诱导 Akt 发生构象变化,从而增强磷酸化和激活。
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规格 价格 库存 数量
5mg
¥280.00
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10mg
¥490.00
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25mg
¥945.00
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50mg
¥1,295.00
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100mg
¥2,135.00
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200mg
¥3,465.00
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500mg
¥6,265.00
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用SC79发表的1篇文献
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • 生物活性
    Discription SC79 is an AKT activator. SC79 binds to the plecktrin homology (PH) domain of Akt that mimics the binding of PtdIns(3,4,5)P3 to induce a conformational change in Akt that enhances phosphorylation and activation.
    Targets
    Target Value
    产品信息
    目录号 A15541
    分子式 C17H17ClN2O5
    分子量 364.78
    CAS号 305834-79-1
    SMILES ClC1=CC=C(OC(N)=C(C(OCC)=O)C2C(C#N)C(OCC)=O)C2=C1
    其他名称 SC 79, SC-79
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 61 mg/mL (167.22 mM)
    Water Insoluble
    Ethanol Warmed: 61 mg/mL (167.22 mM)
    In vivo 2% DMSO+corn oil 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.41 mL 137.07 mL 274.14 mL
    0.5 mM 5.48 mL 27.41 mL 54.83 mL
    1 mM 2.74 mL 13.71 mL 27.41 mL
    5 mM 0.55 mL 2.74 mL 5.48 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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