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SCH 442416

A2A Receptor 拮抗剂

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产品目录号: A12695

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SCH 442416 10mg A12695-10
¥ 1,200.00
SCH 442416 25mg A12695-25
¥ 2,400.00
SCH 442416 50mg A12695-50
¥ 4,800.00
SCH 442416 100mg A12695-100
¥ 9,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SCH 442416 is a selective adenosine A2A receptor antagonist; binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). Displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM).

SCH 442416

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Chemical Information

目录号 A12695
Mechanism of action Antagonist
分子量 389.42
化学分子式 C20H19N7O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 316173-57-6
Synonyms SCH442416, SCH-442416
SMILES code COC1=CC=C(C=C1)CCCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5
化学名称 2-(2-Furanyl)-7-[3-(4-methoxyphenyl?)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]p?yrimidin-5-amine

生物活性

Description
SCH 442416 is a selective adenosine A2A receptor antagonist; binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). Displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.68 mL 128.4 mL 256.79mL
0.5 mM 5.14 mL 25.68 mL 51.36 mL
1 mM 2.57 mL 12.84 mL 25.68 mL
5 mM 0.51 mL 2.57 mL 5.14 mL

*The above data is based on the productmolecular weight 389.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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