SCH 442416

目录号: A12695

A2A Receptor 拮抗剂

SCH 442416

SCH 442416 Chemical Structure

CAS NO. 316173-57-6

SCH 442416是一种选择性的腺苷A2A受体拮抗剂。以高亲和力结合人和大鼠A2A受体(Ki值分别为0.048和0.5 nM)。在体外对hA2A的选择性比hA1高> 23000倍,并且对hA2B和hA3受体的亲和力最小(IC50> 10μM)。

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
25 mg
¥ 2,400.00
50 mg
¥ 4,800.00
100 mg
¥ 9,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SCH 442416是一种选择性的腺苷A2A受体拮抗剂。以高亲和力结合人和大鼠A2A受体(Ki值分别为0.048和0.5 nM)。在体外对hA2A的选择性比hA1高> 23000倍,并且对hA2B和hA3受体的亲和力最小(IC50> 10μM)。
In vitro DMSO 72 mg/mL (184.89 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.68 mL 128.4 mL 256.79 mL
0.5 mM 5.14 mL 25.68 mL 51.36 mL
1 mM 2.57 mL 12.84 mL 25.68 mL
5 mM 0.51 mL 2.57 mL 5.14 mL

*The above data is based on the productmolecular weight 389.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12695
作用机制 Antagonist (拮抗剂)
M. Wt 389.42
Formula C20H19N7O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 316173-57-6
Synonyms SCH442416, SCH-442416
SMILES COC1=CC=C(C=C1)CCCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5

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