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SCH-527123 (Navarixin)


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产品目录号: A11555


产品名 目录号 价格 数量
SCH-527123 5mg A11555-5
¥ 1,200.00
SCH-527123 10mg A11555-10
¥ 2,000.00
SCH-527123 25mg A11555-25
¥ 3,800.00
SCH-527123 50mg A11555-50
¥ 4,800.00



SCH527123 is a potent and selective antagonist of the human CXCR1 and CXCR2 receptors with IC50 of 42 nM and 3 nM, respectively.

SCH-527123 (Navarixin)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 SCH-527123 (Navarixin) 发表的文献 (2)
  • Fu S, .et al. Inhibition of interleukin 8/C?X-C chemokine receptor 1,/2 signaling reduces malignant features in human pancreatic cancer cells, Int J Oncol, 2018, Jul;53(1):349-357 PMID: 29749433
  • Fu S, .et al. Blocking Interleukin-6 and Interleukin-8 Signaling Inhibits Cell Viability, Colony-forming Activity, and Cell Migration in Human Triple-negative Breast Cancer and Pancreatic Cancer Cells, Anticancer Res, 2018, Nov;38(11):6271-6279 PMID: 30396947

Chemical Information

目录号 A11555
Mechanism of action Antagonist
分子量 397.42
化学分子式 C21H23N3O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 473727-83-2
Synonyms SCH 527123, SCH527123
SMILES code CC[C@H](C1=CC=C(O1)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C
化学名称 (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide


SCH527123 is a potent and selective antagonist of the human CXCR1 and CXCR2 receptors with IC50 of 42 nM and 3 nM, respectively.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.16 mL 125.81 mL 251.62mL
0.5 mM 5.03 mL 25.16 mL 50.32 mL
1 mM 2.52 mL 12.58 mL 25.16 mL
5 mM 0.5 mL 2.52 mL 5.03 mL

*The above data is based on the productmolecular weight 397.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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