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SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding, with an IC50 value of 20 nM in rabbit microsomal membranes. Antisecretory and cytoprotective activities.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.06 mL | 180.3 mL | 360.59 mL |
| 0.5 mM | 7.21 mL | 36.06 mL | 72.12 mL |
| 1 mM | 3.61 mL | 18.03 mL | 36.06 mL |
| 5 mM | 0.72 mL | 3.61 mL | 7.21 mL |
*The above data is based on the productmolecular weight 277.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19424 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 277.32 |
| Formula | C17H15N3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 76081-98-6 |
| Synonyms | SCH 28080; SCH-28080 |
| SMILES | N#CCC1=C(C)N=C2C(OCC3=CC=CC=C3)=CC=CN21 |
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