SCH772984

Name: SCH772984
SKU: A12824
Price: 280 CNY
Rating: 5 (6 reviews)

目录号: A12824

ERK 抑制剂

6 篇发表文献

SCH772984 是一种新型的、特异性的 ERK1/2 抑制剂，其 IC50 分别为 4 nM 和 1 nM。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥455.00	现货
5mg	¥595.00	现货
10mg	¥945.00	现货
25mg	¥2,065.00	现货
50mg	¥3,115.00	现货
100mg	¥4,690.00	现货
200mg	¥6,685.00	现货
500mg	¥9,975.00	现货
*10mM 1mL in DMSO**	¥875.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用SCH772984发表的6篇文献

Yuki Shimizu, .et al. , Cancer Lett, 2022, Sep 1;543 PMID: 35724767

Yajun Li, .et al. , Cell Prolif, 2022, Oct;55(10) PMID: 35708050

Sergey A. Dyshlovoy, .et al. , Pharmaceuticals, 2021, 14(10), 949

Sergey A Dyshlovoy, .et al. , Sci Rep, 2020, Aug 6;10(1):13178 PMID: 32764580

Guo X, .et al. , Pflugers Arch, 2018, Jun;470(6):909-921 PMID: 29441404

Takuya Hasegawa, .et al. , FEBS Open Bio, 2017, Aug; 7(8): 1154-1165 PMID: 28781955

生物活性

Discription

SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12824
分子式	C33H33N9O2
分子量	587.68
CAS号	942183-80-4
SMILES	C1CN(C[C@@H]1C(=O)NC2=CC3=C(C=C2)NN=C3C4=CC=NC=C4)CC(=O)N5CCN(CC5)C6=CC=C(C=C6)C7=NC=CC=N7
其他名称	SCH-772984, SCH 772984
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 13 mg/mL (22.12 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+ddH2O	0.5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.02 mL	85.08 mL	170.16 mL
0.5 mM	3.4 mL	17.02 mL	34.03 mL
1 mM	1.7 mL	8.51 mL	17.02 mL
5 mM	0.34 mL	1.7 mL	3.4 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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