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ERK 抑制剂

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产品目录号: A12824


产品名 目录号 价格 数量
SCH772984 5mg A12824-5
¥ 1,100.00
SCH772984 10mg A12824-10
¥ 1,700.00
SCH772984 25mg A12824-25
¥ 3,400.00
SCH772984 50mg A12824-50
¥ 4,800.00



SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 SCH772984 发表的文献 (2)
  • Guo X, .et al. PDGF-induced migration of synthetic vascular smooth muscle cells through c-Src-activated L-type Ca2+ channels with full-length CaV1.2 C-terminus, Pflugers Arch, 2018, Jun;470(6):909-921 PMID: 29441404
  • Takuya Hasegawa, .et al. ErbB2 signaling epigenetically suppresses microRNA坼205 transcription via Ras/Raf/MEK/ERK pathway in breast cancer, FEBS Open Bio, 2017, Aug; 7(8): 1154每1165 PMID: 28781955

Chemical Information

目录号 A12824
Mechanism of action Inhibitor
分子量 587.68
化学分子式 C33H33N9O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 942183-80-4
Synonyms SCH-772984, SCH 772984
SMILES code C1CN(C[C@@H]1C(=O)NC2=CC3=C(C=C2)NN=C3C4=CC=NC=C4)CC(=O)N5CCN(CC5)C6=CC=C(C=C6)C7=NC=CC=N7
化学名称 N/A


SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.
ERK2 (Cell-free assay) ERK1 (Cell-free assay) MEK1 (Cell-free assay)
1 nM4 nM>10 μM


Solubility (25°C)* In vitro DMSO 0.1 mg/mL heating (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.02 mL 85.08 mL 170.16mL
0.5 mM 3.4 mL 17.02 mL 34.03 mL
1 mM 1.7 mL 8.51 mL 17.02 mL
5 mM 0.34 mL 1.7 mL 3.4 mL

*The above data is based on the productmolecular weight 587.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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