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SD 1008

JAK2/STAT3 抑制剂

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产品目录号: A15364

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SD 1008 10mg A15364-10
¥ 1,150.00
SD 1008 50mg A15364-50
¥ 5,150.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SD 1008 is reported to be a JAK2/STAT3 signaling pathway inhibitor which additionally inhibits Src. SD 1008 is noted to induce apoptosis in cell lines that express constitutively active tyrosine-phosphorylated STAT3.

SD 1008

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Chemical Information

目录号 A15364
Mechanism of action Inhibitor
分子量 329.35
化学分子式 C18H19NO5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 960201-81-4
Synonyms SD1008, SD-1008
SMILES code COC(=O)C1C2C=CC(=O)C(C1C(=O)OC)N2CC3=CC=CC=C3.COC(=O)C1C2C=CC(=O)C(C1C(=O)OC)N2CC3=CC=CC=C3
化学名称 (1R,5R,6S,7R)-dimethyl 8-benzyl-2-oxo-8-azabicyclo[3.2.1]oct-3-ene-6,7-dicarboxylate

生物活性

Description
SD 1008 is reported to be a JAK2/STAT3 signaling pathway inhibitor which additionally inhibits Src. SD 1008 is noted to induce apoptosis in cell lines that express constitutively active tyrosine-phosphorylated STAT3.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.36 mL 151.81 mL 303.63mL
0.5 mM 6.07 mL 30.36 mL 60.73 mL
1 mM 3.04 mL 15.18 mL 30.36 mL
5 mM 0.61 mL 3.04 mL 6.07 mL

*The above data is based on the productmolecular weight 329.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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