SD-208
目录号: A14066
TGF-βR 抑制剂
SD-208 是一种强效的口服活性 ATP-竞争性转化生长因子-β受体1 (TGF-βRI) 抑制剂（IC50= 49 nM）；相较于 TGF-βRII 和其他常见激酶，分别显示出超过 100倍 和 17倍 的选择性。
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生物活性
| Discription | SD-208 is a potent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor (IC50= 49 nM); displays > 100-fold and > 17-fold selectivity over TGF-βRII and other common kinases respectively. | |||||
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| Cell Research |
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产品信息
| 目录号 | A14066 |
|---|---|
| 分子式 | C17H10ClFN6 |
| 分子量 | 352.75 |
| CAS号 | 627536-09-8 |
| SMILES | C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F |
| 其他名称 | SD 208, SD208 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | Warmed: 8 mg/mL (22.68 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 1% methylcellulose | 7 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.35 mL | 141.74 mL | 283.49 mL |
| 0.5 mM | 5.67 mL | 28.35 mL | 56.7 mL |
| 1 mM | 2.83 mL | 14.17 mL | 28.35 mL |
| 5 mM | 0.57 mL | 2.83 mL | 5.67 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 SD-208 | SD-208 供应商 | SD-208 花费 | SD-208 生产商 | 订购 SD-208 | SD-208 代理商
| 购买 627536-09-8 | 627536-09-8 供应商 | 627536-09-8 花费 | 627536-09-8 生产商 | 订购 627536-09-8 | 627536-09-8 代理商