SEA0400
SEA0400 是一种新型且选择性的 Na+-Ca2+ 交换抑制剂,其 IC50 为 5-33 nM(抑制培养的神经元、星形胶质细胞和小胶质细胞中的 Na+-依赖性 Ca2+ 吸收)。
Discription | SEA0400 is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia). |
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目录号 | A15236 |
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分子式 | C21H19F2NO3 |
分子量 | 371.38 |
CAS号 | 223104-29-8 |
SMILES | CCOC1=CC(=C(C=C1)OC2=CC=C(C=C2)OCC3=C(C=CC(=C3)F)F)N |
其他名称 | SEA 0400, SEA-0400 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 63 mg/mL (169.63 mM) | |
Water | Insoluble | ||
Ethanol | 63 mg/mL (169.63 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.93 mL | 134.63 mL | 269.27 mL |
0.5 mM | 5.39 mL | 26.93 mL | 53.85 mL |
1 mM | 2.69 mL | 13.46 mL | 26.93 mL |
5 mM | 0.54 mL | 2.69 mL | 5.39 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2