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SEA0400

目录号: A15236
NCX 抑制剂
SEA0400 是一种新型且选择性的 Na+-Ca2+ 交换抑制剂,其 IC50 为 5-33 nM(抑制培养的神经元、星形胶质细胞和小胶质细胞中的 Na+-依赖性 Ca2+ 吸收)。
Grouped product items
规格 价格 库存 数量
1mg
¥175.00
现货
2mg
¥280.00
现货
5mg
¥455.00
现货
10mg
¥840.00
现货
25mg
¥1,645.00
现货
50mg
¥2,625.00
现货
100mg
¥4,130.00
现货
500mg
¥9,205.00
现货
10mM * 1mL in DMSO
¥420.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用SEA0400发表的1篇文献
  • Wakana Shoda, .et al. , PLoS One, 2020, 15(6): e0235360 PMID: 32603346
  • 生物活性
    Discription SEA0400 is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia).
    产品信息
    目录号 A15236
    分子式 C21H19F2NO3
    分子量 371.38
    CAS号 223104-29-8
    SMILES CCOC1=CC(=C(C=C1)OC2=CC=C(C=C2)OCC3=C(C=CC(=C3)F)F)N
    其他名称 SEA 0400, SEA-0400
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 63 mg/mL (169.63 mM)
    Water Insoluble
    Ethanol 63 mg/mL (169.63 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.93 mL 134.63 mL 269.27 mL
    0.5 mM 5.39 mL 26.93 mL 53.85 mL
    1 mM 2.69 mL 13.46 mL 26.93 mL
    5 mM 0.54 mL 2.69 mL 5.39 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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