SEC inhibitor KL-2

Name: SEC inhibitor KL-2
SKU: A19043
Price: 525 CNY
Rating: 5 (288 reviews)

目录号: A19043

SEC 抑制剂

SEC 抑制剂 KL-2（KL-2）是一种肽类模拟先导化合物，是一种强效、选择性的超级延伸复合体（SEC）抑制剂，它能够破坏 SEC 支架蛋白 AFF4 与 P-TEFb 之间的相互作用，导致 Pol II 无法从启动子近端暂停位点释放，从而降低了过程性转录延伸的平均速率。

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Grouped product items
规格	价格	库存
1mg	¥525.00	现货
5mg	¥1,540.00	现货
10mg	¥2,590.00	现货
25mg	¥3,990.00	现货
50mg	¥6,020.00	现货
100mg	¥9,275.00	现货
*10mM 1mL in DMSO**	¥1,295.00	现货
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Data Sheet

SDS

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生物活性

Discription	SEC inhibitor KL-2 (KL-2), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation.

产品信息

目录号	A19043
分子式	C17H13ClFNO3
分子量	333.74
CAS号	900308-51-2
SMILES	O=C(NC1=CC(Cl)=CC=C1C)/C(O)=C/C(C2=CC=C(F)C=C2)=O
其他名称	KL-2
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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