SEL120-34A

Name: SEL120-34A
SKU: A17086
Price: 350 CNY
Rating: 5 (288 reviews)

目录号: A17086

CDK8 抑制剂

SEL120-34A 是一种有效的、选择性的 CDK8 抑制剂，在具有高水平丝氨酸磷酸化的 STAT1 和 STAT5 转录激活域的 AML 细胞中表现活跃。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
5mg	¥1,120.00	现货
10mg	¥1,715.00	现货
25mg	¥2,870.00	现货
50mg	¥4,095.00	现货
100mg	¥5,530.00	现货
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Data Sheet

SDS

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生物活性

Discription

SEL120-34A is a potent and selective CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains.

Targets

Target	Value

产品信息

目录号	A17086
分子式	C15H18Br2N4
分子量	414.145
CAS号	1609522-33-9
SMILES	CC1=C2C3=C(C(Br)=C1Br)CCCN3C(N4CCNCC4)=N2
其他名称	SEL 120-34A, SEL-120-34A, SEL12034A, SEL 12034A, SEL-12034A
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	9 mg/mL (19.97 mM)
	Water	77 mg/mL (170.88 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.15 mL	120.73 mL	241.46 mL
0.5 mM	4.83 mL	24.15 mL	48.29 mL
1 mM	2.41 mL	12.07 mL	24.15 mL
5 mM	0.48 mL	2.41 mL	4.83 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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