SEL24-B489
目录号: A22203
pan-PIM/FLT3 抑制剂
SEL24-B489 HCl 是一种强效的双重全PIM/FLT3抑制剂。
Discription | SEL24-B489 is a potent, type I, orally active dual inhibitor of PIM kinases and FLT3-ITD. It exhibits high affinity for PIM family members, with Kd values of 2 nM for PIM1, 2 nM for PIM2, and 3 nM for PIM3, making it a promising candidate for targeted cancer therapy. |
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目录号 | A22203 |
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分子式 | C15H18Br2N4O2 |
分子量 | 446.14 |
CAS号 | 1616359-00-2 |
SMILES | CC(N1C(C2CCNCC2)=NC3=C([N+]([O-])=O)C(Br)=C(Br)C=C31)C |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2