Seletalisib (UCB-5857)

目录号: A16797

PI3K 抑制剂

Seletalisib (UCB-5857)

Seletalisib (UCB-5857) Chemical Structure

CAS NO. 1362850-20-1

Seletalisib (UCB-5857)是一种新型的PI3Kδ小分子抑制剂,其IC50值为12 nM,相对于其他I类PI3K亚型(介于24-303倍之间),对PI3Kδ具有显著的选择性。

库存: 现货

规格 价格 数量
2 mg
¥ 1,200.00
5 mg
¥ 2,200.00
25 mg
¥ 6,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Seletalisib (UCB-5857)是一种新型的PI3Kδ小分子抑制剂,其IC50值为12 nM,相对于其他I类PI3K亚型(介于24-303倍之间),对PI3Kδ具有显著的选择性。
In vitro DMSO 89 mg/mL (184.32 mM)
Water Insoluble
Ethanol 89 mg/mL (184.32 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.71 mL 103.55 mL 207.1 mL
0.5 mM 4.14 mL 20.71 mL 41.42 mL
1 mM 2.07 mL 10.36 mL 20.71 mL
5 mM 0.41 mL 2.07 mL 4.14 mL

*The above data is based on the productmolecular weight 482.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16797
作用机制 Inhibitor (抑制剂)
M. Wt 482.85
Formula C23H14ClF3N6O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1362850-20-1
Synonyms UCB-5857; UCB 5857; UCB5857; Seletalisib
SMILES FC(F)(F)[C@@H](C1=CC2=CC=CC(Cl)=C2N=C1C3=CC=C[N+]([O-])=C3)NC4=C5C(C=CC=N5)=NC=N4

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