Seletalisib (UCB-5857)

Name: Seletalisib (UCB-5857)
SKU: A16797
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A16797

PI3K 抑制剂

Seletalisib 是一种新型小分子 PI3Kδ 抑制剂，其 IC50 值为 12 nM，并且相对于其他 I 类 PI3K 同型体显示出显著的选择性（选择性在 24 至 303 倍之间）。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
2mg	¥455.00	现货
5mg	¥805.00	现货
10mg	¥1,330.00	现货
25mg	¥2,380.00	现货
50mg	¥3,430.00	现货
100mg	¥4,830.00	现货
*10mM 1mL in DMSO**	¥840.00	现货
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Data Sheet

SDS

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生物活性

Discription

Seletalisib is a novel small-molecule inhibitor of PI3Kδ with an IC50 value of 12 nM and shows significant selectivity to PI3Kδ with respect to the other class I PI3K isoforms (between 24- and 303-fold).

Targets

Target	Value

产品信息

目录号	A16797
分子式	C23H14ClF3N6O
分子量	482.85
CAS号	1362850-20-1
SMILES	FC(F)(F)[C@@H](C1=CC2=CC=CC(Cl)=C2N=C1C3=CC=C[N+]([O-])=C3)NC4=C5C(C=CC=N5)=NC=N4
其他名称	UCB-5857; UCB 5857; UCB5857; Seletalisib
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (184.32 mM)
	Water	Insoluble
	Ethanol	89 mg/mL (184.32 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.71 mL	103.55 mL	207.1 mL
0.5 mM	4.14 mL	20.71 mL	41.42 mL
1 mM	2.07 mL	10.36 mL	20.71 mL
5 mM	0.41 mL	2.07 mL	4.14 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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