Selinexor trans-isomer
目录号: A22648
CRM1-selective 抑制剂
Selinexor trans-isomer 是 Selinexor 或 KPT-330 的反式异构体,它是一种选择性抑制核输出的 CRM1 抑制剂。它抑制蛋白质从核内运输,并在间皮瘤细胞中诱导细胞周期阻滞和凋亡。
Discription | Selinexor trans-isomer is a trans-isomer of Selinexor or KPT-330, which is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells. |
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目录号 | A22648 |
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分子式 | C17H11F6N7O |
分子量 | 443.31 |
CAS号 | 1421923-86-5 |
SMILES | O=C(NNC1=NC=CN=C1)/C=C/N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2