Selonsertib

Name: Selonsertib
SKU: A15991
Price: 175 CNY
Rating: 5 (2 reviews)

目录号: A15991

ASK1 抑制剂

2 篇发表文献

Selonsertib 是一种口服生物利用度的 凋亡信号调节激酶1（ASK1）抑制剂，具有潜在的抗炎、抗肿瘤和抗纤维化活性。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥385.00	现货
10mg	¥595.00	现货
25mg	¥1,050.00	现货
50mg	¥1,365.00	现货
100mg	¥2,485.00	现货
200mg	¥4,060.00	现货
500mg	¥5,880.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Selonsertib发表的2篇文献

Lisa M Kim, .et al. , Cancer Res, 2022, Sep 2;82(17):3045-3057 PMID: 35792658

Luwa Yuan, .et al. , Sci Rep, 2019, 9:11156 PMID: 31371790

生物活性

Discription

Selonsertib is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15991
分子式	C24H24FN7O
分子量	445.5
CAS号	1448428-04-3
SMILES	O=C(NC1=NC(C2=NN=CN2C(C)C)=CC=C1)C3=CC(N4C=C(C5CC5)N=C4)=C(C)C=C3F
其他名称	GS-4997, GS4997, GS 4997
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	34 mg/mL (76.31 mM)
	Water	Insoluble
	Ethanol	23 mg/mL (51.63 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.45 mL	112.23 mL	224.47 mL
0.5 mM	4.49 mL	22.45 mL	44.89 mL
1 mM	2.24 mL	11.22 mL	22.45 mL
5 mM	0.45 mL	2.24 mL	4.49 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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