Semorinemab (RG 6100) is a humanized IgG4 monoclonal antibody designed to specifically target the N-terminal region of the Tau protein, encompassing amino acid residues 6-23. This antibody exhibits a high affinity for human Tau, with a dissociation constant (Kd) of 3.8 nM, indicating robust binding efficiency. Semorinemab is primarily utilized in the investigation of Alzheimer's Disease, serving as a critical tool in research focused on the pathophysiology and potential therapeutic interventions for tauopathies.
Semorinemab (RG 6100) is a humanized IgG4 monoclonal antibody designed to specifically target the N-terminal region of the Tau protein, encompassing amino acid residues 6-23. This antibody exhibits a high affinity for human Tau, with a dissociation constant (Kd) of 3.8 nM, indicating robust binding efficiency. Semorinemab is primarily utilized in the investigation of Alzheimer's Disease, serving as a critical tool in research focused on the pathophysiology and potential therapeutic interventions for tauopathies.
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