Sevirumab (MSL-109) is a human IgG1 monoclonal antibody designed to neutralize cytomegalovirus (CMV). This antibody specifically targets CMV glycoprotein H (gH) complexes, effectively inhibiting viral replication. It demonstrates potent antiviral activity with an EC50 value of 0.3 ??g/mL, making it a valuable tool for research into CMV pathogenesis and therapeutic intervention.
Sevirumab (MSL-109) is a human IgG1 monoclonal antibody designed to neutralize cytomegalovirus (CMV). This antibody specifically targets CMV glycoprotein H (gH) complexes, effectively inhibiting viral replication. It demonstrates potent antiviral activity with an EC50 value of 0.3 ??g/mL, making it a valuable tool for research into CMV pathogenesis and therapeutic intervention.
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