Seviteronel

目录号: A20996

CYP17 lyase inhibitor

Seviteronel

Seviteronel Chemical Structure

CAS NO. 1610537-15-9

Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition.

库存: 现货

规格 价格 数量
5 mg
¥ 3,780.00
10 mg
¥ 6,510.00
50 mg
¥ 19,320.00
100 mg
¥ 38,640.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.04 mL 125.21 mL 250.41 mL
0.5 mM 5.01 mL 25.04 mL 50.08 mL
1 mM 2.5 mL 12.52 mL 25.04 mL
5 mM 0.5 mL 2.5 mL 5.01 mL

*The above data is based on the productmolecular weight 399.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A20996
作用机制 Inhibitor (抑制剂)
M. Wt 399.34
Formula C18H17F4N3O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1610537-15-9
Synonyms VT-464, VT464, VT 464
SMILES FC(F)OC1=C(OC(F)F)C=C(C=CC([C@](C2=CNN=N2)(C(C)C)O)=C3)C3=C1

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