Seviteronel

Name: Seviteronel
SKU: A20996
Price: 735 CNY
Rating: 5 (288 reviews)

目录号: A20996

CYP17 lyase 抑制剂

Seviteronel（VT-464）是一种强效的CYP17裂解酶抑制剂（h-Lyase IC50=69 nM），在体外实验中显示出卓越的裂解酶/羟化酶选择性（约10倍），并在仓鼠的雄激素生物合成抑制模型中展示了口服活性。

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Grouped product items
规格	价格	库存
1mg	¥735.00	现货
5mg	¥1,855.00	现货
10mg	¥2,730.00	现货
25mg	¥4,690.00	现货
50mg	¥6,650.00	现货
100mg	¥8,925.00	现货
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Data Sheet

SDS

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生物活性

Discription	Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition.

产品信息

目录号	A20996
分子式	C18H17F4N3O3
分子量	399.34
CAS号	1610537-15-9
SMILES	FC(F)OC1=C(OC(F)F)C=C(C=CC([C@](C2=CNN=N2)(C(C)C)O)=C3)C3=C1
其他名称	VT-464, VT464, VT 464
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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