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SF1126

Pan PI3K 抑制剂

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产品目录号: A12704

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SF1126 5mg A12704-5
¥ 3,500.00
SF1126 10mg A12704-10
¥ 6,500.00
SF1126 25mg A12704-25
¥ 12,000.00
SF1126 50mg A12704-50
¥ 20,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities.

SF1126

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Chemical Information

目录号 A12704
Mechanism of action Inhibitor
分子量 852.84
化学分子式 C39H48N8O14
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 936487-67-1
Synonyms SF 1126, SF-1126
SMILES code C1COCC[N+]1(COC(=O)CCC(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)[O-])C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4
化学名称 (8S,14S,17S)-14-(carboxymethyl)-8-(3-guanidinopropyl)-17-(hydroxymethyl)-3,6,9,12,15-pentaoxo-1-(4-(4-oxo-8-phenyl-4H-chromen-2-yl)morpholino-4-ium)-2-oxa-7,10,13,16-tetraazaoctadecan-18-oate

生物活性

Description
SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.73 mL 58.63 mL 117.26mL
0.5 mM 2.35 mL 11.73 mL 23.45 mL
1 mM 1.17 mL 5.86 mL 11.73 mL
5 mM 0.23 mL 1.17 mL 2.35 mL

*The above data is based on the productmolecular weight 852.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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