SF2523

Name: SF2523
SKU: A20557

目录号: A20557

PI3K inhibitor

Product Citations (1)

SF2523 Chemical Structure

CAS NO. 1174428-47-7

SF2523 is a highly selective and potent inhibitor of PI3K with IC50s of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively.

库存：现货

规格	价格	数量
1 mg	￥ 540.00
5 mg	￥ 1,620.00
10 mg	￥ 2,760.00
50 mg	￥ 8,280.00

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生物活性

SF2523 is a highly selective and potent inhibitor of PI3K with IC50s of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively.

溶解度 *

In vitro	DMSO	29 mg/mL (78.08 mM)
	Water	Insoluble
	Ethanol	7 mg/mL (18.84 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.92 mL	134.62 mL	269.24 mL
0.5 mM	5.38 mL	26.92 mL	53.85 mL
1 mM	2.69 mL	13.46 mL	26.92 mL
5 mM	0.54 mL	2.69 mL	5.38 mL

*The above data is based on the productmolecular weight 371.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20557
M. Wt	371.41
Formula	C19H17NO5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1174428-47-7
Synonyms	SF 2523, SF-2523
SMILES	O=C1C=C(N2CCOCC2)OC3=C1SC=C3C4=CC=C(OCCO5)C5=C4