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SGC 707

促销

PRMT3 抑制剂

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产品目录号: A15450

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SGC 707 10mg A15450-10
¥ 900.00
SGC 707 25mg A15450-25
¥ 1,800.00
SGC 707 50mg A15450-50
¥ 3,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SGC 707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets.

SGC 707

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Chemical Information

目录号 A15450
Mechanism of action Inhibitor
分子量 298.3
化学分子式 C16H18N4O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1687736-54-4
Synonyms SGC707, SGC-707
SMILES code C1CCN(C1)C(=O)CNC(=O)NC2=CC3=C(C=C2)C=NC=C3
化学名称 N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-urea

生物活性

Description
SGC 707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets.
Targets
PRMT3 PRMT3
31 nM53 nM(Kd)

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.52 mL 167.62 mL 335.23mL
0.5 mM 6.7 mL 33.52 mL 67.05 mL
1 mM 3.35 mL 16.76 mL 33.52 mL
5 mM 0.67 mL 3.35 mL 6.7 mL

*The above data is based on the productmolecular weight 298.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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