SGI 1027

目录号: A14120

DNMT 抑制剂

SGI 1027 Chemical Structure

CAS NO. 1020149-73-8

SGI 1027 is a DNMT inhibitor with IC50 of 6, 8, 7.5 uM for DNMT1, DNMT3A, and DNMT3B, respectively.

库存: 现货

规格 价格 数量
10 mg
¥ 900.00
25 mg
¥ 1,800.00
50 mg
¥ 3,100.00
10mM * 1mL in DMSO
¥ 1,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SGI 1027 is a DNMT inhibitor with IC50 of 6, 8, 7.5 uM for DNMT1, DNMT3A, and DNMT3B, respectively.
靶点信息
DNMT1 (Cell-free assay) DNMT3B (Cell-free assay) DNMT3A (Cell-free assay)
6 μM7.5 μM8 μM
In vitro DMSO 92 mg/mL (199.34 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.67 mL 108.34 mL 216.68 mL
0.5 mM 4.33 mL 21.67 mL 43.34 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14120
MECHANISM OF ACTION Inhibitor
M. Wt 461.52
Formula C27H23N7O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1020149-73-8
Synonyms SGI-1027, SGI1027
SMILES CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)NC4=CC=NC5=CC=CC=C54

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