SGI-7079

目录号: A15864

Axl inhibitor

SGI-7079

SGI-7079 Chemical Structure

CAS NO. 1239875-86-5

SGI-7079 ,a novel selective Axl inhibitor, inhibits tumor growth in a dose dependent manner and is a potential therapeutic target for overcoming EGFR inhibitor resistance.

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
25 mg
¥ 2,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SGI-7079 ,a novel selective Axl inhibitor, inhibits tumor growth in a dose dependent manner and is a potential therapeutic target for overcoming EGFR inhibitor resistance.
Targets
Target Value
Met
Mer
YES
RET
FLT3
AxlIC50: 58nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.95 mL 109.76 mL 219.52 mL
0.5 mM 4.39 mL 21.95 mL 43.9 mL
1 mM 2.2 mL 10.98 mL 21.95 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15864
MECHANISM OF ACTION Inhibitor
M. Wt 455.53
Formula C26H26FN7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1239875-86-5
Synonyms SGI7079, SGI 7079
SMILES N#CCC1=CC=CC(C2=C3C(NC=C3C)=NC(NC4=CC=C(N5CCN(C)CC5)C(F)=C4)=N2)=C1

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