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SHIN1 (RZ-2994) is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor with IC50s of 5 and 13 nM, respectively, in an in vitro assay.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.97 mL | 124.85 mL | 249.71 mL |
| 0.5 mM | 4.99 mL | 24.97 mL | 49.94 mL |
| 1 mM | 2.5 mL | 12.49 mL | 24.97 mL |
| 5 mM | 0.5 mL | 2.5 mL | 4.99 mL |
*The above data is based on the productmolecular weight 400.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19228 |
|---|---|
| M. Wt | 400.47 |
| Formula | C24H24N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2146095-85-2 |
| Synonyms | SHIN 1, SHIN-1 |
| SMILES | OCC1=CC(C2=CC=CC=C2)=CC(C3(C(C(C)=NN4)=C4OC(N)=C3C#N)C(C)C)=C1 |
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