Sifalimumab (MEDI-545) is a monoclonal antibody that targets and neutralizes multiple subtypes of interferon-alpha (IFN??), a key cytokine involved in the pathogenesis of autoimmune disorders. By binding to IFN??, Sifalimumab effectively suppresses abnormal immune responses. This antibody is particularly relevant for research into systemic lupus erythematosus (SLE), providing a valuable tool for investigating the role of IFN?? in SLE pathophysiology and for exploring potential therapeutic interventions.
Sifalimumab (MEDI-545) is a monoclonal antibody that targets and neutralizes multiple subtypes of interferon-alpha (IFN??), a key cytokine involved in the pathogenesis of autoimmune disorders. By binding to IFN??, Sifalimumab effectively suppresses abnormal immune responses. This antibody is particularly relevant for research into systemic lupus erythematosus (SLE), providing a valuable tool for investigating the role of IFN?? in SLE pathophysiology and for exploring potential therapeutic interventions.
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