Sildenafil citrate
目录号: A10841
PDE5 抑制剂
枸橼酸西地那非是一种强效的磷酸二酯酶5型(PDE5)抑制剂,其半抑制浓度(IC50)为5.22纳摩尔。
| Discription | Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM. | ||
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| 目录号 | A10841 |
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| 分子式 | C28H38N6O11S |
| 分子量 | 666.7 |
| CAS号 | 171599-83-0 |
| SMILES | O=C1C(N(C)N=C2CCC)=C2N=C(C3=CC(S(=O)(N4CCN(C)CC4)=O)=CC=C3OCC)N1.O=C(CC(C(O)=O)(O)CC(O)=O)O |
| 其他名称 | UK-92480 citrate |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Warmed: 20 mg/mL (29.99 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15 mL | 75 mL | 149.99 mL |
| 0.5 mM | 3 mL | 15 mL | 30 mL |
| 1 mM | 1.5 mL | 7.5 mL | 15 mL |
| 5 mM | 0.3 mL | 1.5 mL | 3 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2