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Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from the fruits and twigs of Aglaia foveolata. Silvestrol induces autophagy and caspase-mediated apoptosis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.28 mL | 76.38 mL | 152.75 mL |
| 0.5 mM | 3.06 mL | 15.28 mL | 30.55 mL |
| 1 mM | 1.53 mL | 7.64 mL | 15.28 mL |
| 5 mM | 0.31 mL | 1.53 mL | 3.06 mL |
*The above data is based on the productmolecular weight 654.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11574 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 654.66 |
| Formula | C34H38O13 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 697235-38-4 |
| Synonyms | (-)-Silvestrol |
| SMILES | O=C([C@H]([C@H]1C2=CC=CC=C2)[C@@H](O)[C@]3(O)[C@@]1(C4=CC=C(OC)C=C4)OC5=CC(O[C@@H]6O[C@@H]([C@H](O)CO)CO[C@H]6OC)=CC(OC)=C35)OC |
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