Simvastatin
目录号: A10845
HMG-CoA reductase 抑制剂
Simvastatin(MK 733)是一种与HMG-CoA还原酶具有竞争性抑制作用的药物,其Ki值为0.2 nM。
Discription | Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. | |||||
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Cell Research |
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目录号 | A10845 |
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分子式 | C25H38O5 |
分子量 | 418.57 |
CAS号 | 79902-63-9 |
SMILES | CCC(C)(C)C(O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(O3)=O)[C@@]12[H])=O |
其他名称 | MK 733, MK-733, MK733 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 71 mg/mL (169.62 mM) | |
Water | Insoluble | ||
Ethanol | 71 mg/mL (169.62 mM) | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween80+ddH2O | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.89 mL | 119.45 mL | 238.91 mL |
0.5 mM | 4.78 mL | 23.89 mL | 47.78 mL |
1 mM | 2.39 mL | 11.95 mL | 23.89 mL |
5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2