Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody that targets CD2, a cell surface antigen predominantly expressed on T cells. This antibody functions by depleting T cells, reducing their activation, and inhibiting their proliferation. Additionally, Siplizumab promotes the enrichment of na??ve and bona fide regulatory T cells. It is utilized primarily in research focused on immunological tolerance, autoimmunity, and transplantation immunology.
Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody that targets CD2, a cell surface antigen predominantly expressed on T cells. This antibody functions by depleting T cells, reducing their activation, and inhibiting their proliferation. Additionally, Siplizumab promotes the enrichment of na??ve and bona fide regulatory T cells. It is utilized primarily in research focused on immunological tolerance, autoimmunity, and transplantation immunology.
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