SIS-17

Name: SIS-17
SKU: A18463
Price: 350 CNY
Rating: 5 (288 reviews)

目录号: A18463

HDAC 11 抑制剂

SIS17 是一种强效且选择性的 HDAC 11 抑制剂，其 IC50 值为 0.83 μM。SIS17 在细胞中活跃，并抑制了已知的 HDAC11 底物丝氨酸羟甲基转移酶2的去肉豆蔻酰化作用，而不抑制其他 HDACs。

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规格	价格	库存
5mg	¥350.00	现货
10mg	¥630.00	现货
25mg	¥1,260.00	现货
50mg	¥2,205.00	现货
100mg	¥3,535.00	现货
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Data Sheet

SDS

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生物活性

Discription

SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.

Targets

Target	Value

产品信息

目录号	A18463
分子式	C21H38N2OS
分子量	366.6
CAS号	2374313-54-7
SMILES	O=C(C1=CC=CS1)NNCCCCCCCCCCCCCCCC
其他名称	SIS-17; SIS 17; SIS17;
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	68 mg/mL (185.48 mM)
	Water	Insoluble
	Ethanol	17 mg/mL (46.36 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.28 mL	136.39 mL	272.78 mL
0.5 mM	5.46 mL	27.28 mL	54.56 mL
1 mM	2.73 mL	13.64 mL	27.28 mL
5 mM	0.55 mL	2.73 mL	5.46 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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