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Smad3 抑制剂

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产品目录号: A16065


产品名 目录号 价格 数量
SIS3 5mg A16065-5
¥ 1,000.00
SIS3 10mg A16065-10
¥ 1,800.00
SIS3 25mg A16065-25
¥ 3,130.00



SIS3 is a novel specific inhibitor of Smad3. It has effect on transforming growth factor-beta1-induced extracellular matrix expression.





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Chemical Information

目录号 A16065
Mechanism of action Inhibitor
分子量 489.99
化学分子式 C28H27N3O3.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 521984-48-5
Synonyms SIS 3
SMILES code CN1C(C2=CC=CC=C2)=C(C3=C1N=CC=C3)/C([H])=C([H])/C(N4CCC5=CC(OC)=C(OC)C=C5C4)=O.Cl
化学名称 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline hydrochloride


SIS3 is a novel specific inhibitor of Smad3. It has effect on transforming growth factor-beta1-induced extracellular matrix expression.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.41 mL 102.04 mL 204.09mL
0.5 mM 4.08 mL 20.41 mL 40.82 mL
1 mM 2.04 mL 10.2 mL 20.41 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 489.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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