SIS3

Name: SIS3
SKU: A16065
Price: 210 CNY
Rating: 5 (2 reviews)

目录号: A16065

Smad3 抑制剂

2 篇发表文献

SIS3 是一种新型的特异性 Smad3 抑制剂。它对转化生长因子-beta1诱导的细胞外基质表达有影响。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥665.00	现货
10mg	¥1,190.00	现货
25mg	¥2,135.00	现货
50mg	¥3,710.00	现货
100mg	¥5,320.00	现货
500mg	¥10,815.00	现货
*10mM 1mL in DMSO**	¥805.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用SIS3发表的2篇文献

Miao Deng, .et al. , ACS Appl Mater Interfaces, 2021, Apr 21;13(15):18033-18046 PMID: 33834754

Wei P, .et al. , Cell Death Dis, 2019, Sep 11;10(9):670 PMID: 31511493

生物活性

Discription

SIS3 is a novel specific inhibitor of Smad3. It has effect on transforming growth factor-beta1-induced extracellular matrix expression.

Targets

Target	Value

产品信息

目录号	A16065
分子式	C28H27N3O3.HCl
分子量	489.99
CAS号	521984-48-5
SMILES	CN1C(C2=CC=CC=C2)=C(C3=C1N=CC=C3)/C([H])=C([H])/C(N4CCC5=CC(OC)=C(OC)C=C5C4)=O.Cl
其他名称	SIS 3
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	92 mg/mL (187.76 mM)
	Water	Insoluble
	Ethanol	23 mg/mL (46.94 mM)
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.41 mL	102.04 mL	204.09 mL
0.5 mM	4.08 mL	20.41 mL	40.82 mL
1 mM	2.04 mL	10.2 mL	20.41 mL
5 mM	0.41 mL	2.04 mL	4.08 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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