Sitaxsentan sodium (TBC-11251)

目录号: A11564

ETA receptor antagonist

Sitaxsentan sodium (TBC-11251) Chemical Structure

CAS NO. 210421-74-2

Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and Ki of 1.4 nM and 0.43 nM, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 650.00
10 mg
¥ 1,100.00
25 mg
¥ 2,200.00
50 mg
¥ 3,600.00
10mM * 1mL in DMSO
¥ 1,450.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and Ki of 1.4 nM and 0.43 nM, respectively.
Targets
ET-A ET-A
0.43 nM(Ki)1.4 nM
In vitro DMSO 40 mg/mL (83.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol 20 mg/mL (41.93 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.97 mL 104.85 mL 209.69 mL
0.5 mM 4.19 mL 20.97 mL 41.94 mL
1 mM 2.1 mL 10.48 mL 20.97 mL
5 mM 0.42 mL 2.1 mL 4.19 mL

*The above data is based on the productmolecular weight 476.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11564
MECHANISM OF ACTION Antagonist
M. Wt 476.89
Formula C18H14ClN2NaO6S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 210421-74-2
Synonyms N/A
SMILES CC1=CC2=C(C=C1CC(=O)C3=C(C=CS3)S(=O)(=O)[N-]C4=C(C(=NO4)C)Cl)OCO2.[Na+]

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