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SJ 172550

MDMX 抑制剂

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产品目录号: A15352

库存状态:中国现货中国现货

产品名 目录号 价格 数量
SJ 172550 10mg A15352-10
¥ 1,100.00
SJ 172550 50mg A15352-50
¥ 4,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

SJ 172550 is the first MDMX inhibitor with EC50 of 0.84 uM; binds reversibly to MDMX and effectively kills retinoblastoma cells in which the expression of MDMX is amplified.

SJ 172550

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Chemical Information

目录号 A15352
Mechanism of action Inhibitor
分子量 428.87
化学分子式 C22H21ClN2O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 431979-47-4
Synonyms SJ172550, SJ-172550
SMILES code CCOC1=C(C(=CC(=C1)C=C2C(=NN(C2=O)C3=CC=CC=C3)C)Cl)OCC(=O)OC
化学名称 methyl 2-[2-chloro-6-ethoxy-4-[(3-methyl-5-oxo-1-phenylpyrazol-4-ylidene)methyl]phenoxy]acetate

生物活性

Description
SJ 172550 is the first MDMX inhibitor with EC50 of 0.84 uM; binds reversibly to MDMX and effectively kills retinoblastoma cells in which the expression of MDMX is amplified.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.32 mL 116.59 mL 233.17mL
0.5 mM 4.66 mL 23.32 mL 46.63 mL
1 mM 2.33 mL 11.66 mL 23.32 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 428.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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