SJFα

Name: SJFα
SKU: A18602
Price: 560 CNY
Rating: 5 (288 reviews)

目录号: A18602

13-atom linker PROTAC

SJFα 是一种含有 13 个原子的连接体 PROTAC。SJFα 以 DC50 为 7.16 nM 降解 p38α，但在降解 p38δ 方面效果较差（DC50=299 nM），并且在高达 2.5 µM 的浓度下不降解其他 p38 异构体（β 和 γ）。

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Grouped product items
规格	价格	库存
1mg	¥560.00	现货
5mg	¥1,435.00	现货
10mg	¥2,730.00	现货
25mg	¥5,880.00	现货
50mg	¥10,395.00	现货
100mg	¥18,760.00	现货
*10mM 1mL in DMSO**	¥3,430.00	现货
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Data Sheet

SDS

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生物活性

Discription

SJFα is a 13-atom linker PROTAC. SJFα degrades p38α with a DC50 of 7.16??nM, but is far less effective at degrading p38δ (DC50=299?nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5??M.

Targets

Target	Value

产品信息

目录号	A18602
分子式	C59H67F2N7O11S
分子量	1120.27
CAS号	2254609-27-1
SMILES	FC1=CC=C(NC(C2(CC2)C(NC3=CC(F)=C(OC4=C(C=C(OC)C(OCCCCOCCCCOCC(N[C@@H](C(C)(C)C)C(N5[C@H](C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)C[C@@H](O)C5)=O)=O)=C8)C8=NC=C4)C=C3)=O)=O)C=C1
其他名称	SJF-α, SJF α
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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