SKLB-23bb

Name: SKLB-23bb
SKU: A18339
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A18339

HDAC6 抑制剂

SKLB-23bb 是一种针对 HDAC6 的强效和选择性抑制剂，其 IC50 为 17 nM，并且相对于 HDAC1（IC50=422 nM）和 HDAC8（IC50=3398 nM）分别显示出 25 倍和 200 倍的选择性。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
5mg	¥945.00	现货
10mg	¥1,400.00	现货
25mg	¥2,310.00	现货
50mg	¥3,255.00	现货
100mg	¥4,515.00	现货
200mg	¥6,160.00	现货
*10mM 1mL in DMSO**	¥1,050.00	现货
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Data Sheet

SDS

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生物活性

Discription

SKLB-23bb is a potent and selective inhibitor for HDAC6 with an IC50 of 17 nM and shows 25-fold and 200-fold selectivity relative to HDAC1 (IC50=422 nM) and HDAC8 (IC50=3398 nM), respectively.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A18339
分子式	C21H24N4O4
分子量	396.447
CAS号	1815580-06-3
SMILES	O=C(NO)CCCOC1=CC(N(C)C2=C3C=CC=CC3=NC(C)=N2)=CC=C1OC
其他名称	SKLB 23bb, SKLB23bb
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	76 mg/mL (191.7 mM)
	Water	Insoluble
	Ethanol	76 mg/mL (191.7 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.22 mL	126.12 mL	252.24 mL
0.5 mM	5.04 mL	25.22 mL	50.45 mL
1 mM	2.52 mL	12.61 mL	25.22 mL
5 mM	0.5 mL	2.52 mL	5.04 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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