SLx-2119 (KD025)

目录号: A15239

ROCK2 Inhibitor

SLx-2119 (KD025) Chemical Structure

CAS NO. 911417-87-3

SLx-2119 is a small molecule and selective inhibitor of ROCK2 with IC50 of 105 nM; > 200 fold selecivity over ROCK1(IC50 =24 uM).

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 950.00
100 mg
¥ 4,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SLx-2119 is a small molecule and selective inhibitor of ROCK2 with IC50 of 105 nM; > 200 fold selecivity over ROCK1(IC50 =24 uM).
Targets
ROCK2 ROCK2
41 nM(Ki)60 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.1 mL 110.49 mL 220.99 mL
0.5 mM 4.42 mL 22.1 mL 44.2 mL
1 mM 2.21 mL 11.05 mL 22.1 mL
5 mM 0.44 mL 2.21 mL 4.42 mL

*The above data is based on the productmolecular weight 452.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15239
MECHANISM OF ACTION Inhibitor
M. Wt 452.51
Formula C26H24N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 911417-87-3
Synonyms SLx 2119, SLx2119, ROCK inhibitor, KD-025
SMILES CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C(C=C4)NN=C5

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