SLx-2119 (KD025)

Name: SLx-2119 (KD025)
SKU: A15239
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A15239

ROCK2 抑制剂

SLx-2119 是一种小分子，并且是 ROCK2 的选择性抑制剂，其 IC50 为 105 nM；对 ROCK1 的选择性超过 200 倍（IC50 = 24 uM）。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥595.00	现货
25mg	¥1,120.00	现货
50mg	¥1,785.00	现货
100mg	¥2,730.00	现货
500mg	¥6,545.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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Data Sheet

SDS

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生物活性

Discription

SLx-2119 is a small molecule and selective inhibitor of ROCK2 with IC50 of 105 nM; > 200 fold selecivity over ROCK1(IC50 =24 uM).

Targets

Target	Value

产品信息

目录号	A15239
分子式	C26H24N6O2
分子量	452.51
CAS号	911417-87-3
SMILES	CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C(C=C4)NN=C5
其他名称	SLx 2119, SLx2119, ROCK inhibitor, KD-025
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	84 mg/mL (185.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+35% PEG 300+2%Tween 80+ddH2O	6 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.1 mL	110.49 mL	220.99 mL
0.5 mM	4.42 mL	22.1 mL	44.2 mL
1 mM	2.21 mL	11.05 mL	22.1 mL
5 mM	0.44 mL	2.21 mL	4.42 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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