SM-164

Name: SM-164
SKU: A15800
Price: 770 CNY
Rating: 5 (3 reviews)

目录号: A15800

cIAP-2 拮抗剂

3 篇发表文献

SM-164 是一种高效的细胞渗透性双价 Smac 模拟物，它与 XIAP 蛋白结合的 Ki 值为 0.56 nM，与 cIAP-1 和 cIAP-2 蛋白结合的 Ki 值分别为 0.31 nM 和 1.1 nM。

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Grouped product items
规格	价格	库存
1mg	¥770.00	现货
2mg	¥1,155.00	现货
5mg	¥1,925.00	现货
10mg	¥3,045.00	现货
25mg	¥4,970.00	现货
50mg	¥6,930.00	现货
100mg	¥12,460.00	现货
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Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用SM-164发表的3篇文献

Antonella Antignani, .et al. , FASEB J, 2023, Dec;37(12):e23292 PMID: 37971407

Hanna Yuk, .et al. , Antioxidants (Basel), 2021, Aug 25;10(9):1347 PMID: 34572979

Caroline Moerke, .et al. , Cell Death Differ, 2018, Nov 15 PMID: 30442947

生物活性

Discription

SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15800
分子式	C62H84N14O6
分子量	1121.42
CAS号	957135-43-2
SMILES	CC(C(=O)NC1CCCCC2CCC(N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)C(C7=CC=CC=C7)NC(=O)C8CCC9N8C(=O)C(CCCC9)NC(=O)C(C)NC)NC
其他名称	SM 164, SM164
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	3 mg/mL (2.67 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.92 mL	44.59 mL	89.17 mL
0.5 mM	1.78 mL	8.92 mL	17.83 mL
1 mM	0.89 mL	4.46 mL	8.92 mL
5 mM	0.18 mL	0.89 mL	1.78 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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