SN 38

Name: SN 38
SKU: A12011
Price: 210 CNY
Rating: 5 (5 reviews)

目录号: A12011

DNA topoisomerase 抑制剂

5 篇发表文献

SN 38 是伊立替康（一种 拓扑异构酶 I 抑制剂 喋呤类似物）的活性代谢产物。

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Grouped product items
规格	价格	库存
25mg	¥210.00	现货
50mg	¥350.00	现货
100mg	¥490.00	现货
250mg	¥805.00	现货
500mg	¥1,015.00	现货
*10mM 1mL in DMSO**	¥595.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用SN 38发表的5篇文献

Akari Shiraishi, .et al. , Biochem Biophys Res Commun, 2024, Jun 11:725:150255 PMID: 38897043

Sarigama Rajesh, .et al. , Pharmaceutics, 2022, Oct 12;14(10):2175 PMID: 36297610

Chen JC, .et al. , Biomolecules, 2019, Sep 9;9(9) PMID: 31505885

Alibolandi M, .et al. , Artif Cells Nanomed Biotechnol, 2018, May 27:1-12 PMID: 29806500

Bar-Zeev M, .et al. , Eur J Pharm Biopharm, 2018, Dec;133:240-249 PMID: 30367935

生物活性

Discription

SN 38 is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12011
分子式	C22H20N2O5
分子量	392.4
CAS号	86639-52-3
SMILES	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)O
其他名称	7-Ethyl-10-hydroxycamptothecin, SN38, SN-38
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	20 mg/mL (50.96 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.48 mL	127.42 mL	254.84 mL
0.5 mM	5.1 mL	25.48 mL	50.97 mL
1 mM	2.55 mL	12.74 mL	25.48 mL
5 mM	0.51 mL	2.55 mL	5.1 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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