SN 38

目录号: A12011

DNA topoisomerase Inhibitor

SN 38

SN 38 Chemical Structure

CAS NO. 86639-52-3

SN 38 is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor).

库存: 现货

规格 价格 数量
50 mg
¥ 600.00
100 mg
¥ 800.00
250 mg
¥ 1,600.00
10mM * 1mL in DMSO
¥ 850.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SN 38 is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor).
Targets
Topo I (Cell-free assay)
In vitro DMSO 21 mg/mL (53.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.48 mL 127.42 mL 254.84 mL
0.5 mM 5.1 mL 25.48 mL 50.97 mL
1 mM 2.55 mL 12.74 mL 25.48 mL
5 mM 0.51 mL 2.55 mL 5.1 mL

*The above data is based on the productmolecular weight 392.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12011
MECHANISM OF ACTION Inhibitor
M. Wt 392.4
Formula C22H20N2O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 86639-52-3
Synonyms 7-Ethyl-10-hydroxycamptothecin, SN38, SN-38
SMILES CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)O

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